From the 1841 Boston Alamanac:
25 August 1840
During a heavy shower, a new unfinished house on the South Cove land, near Front street [soon to be Harrison Avenue], owned by Mr. Nathan Wheeler, was struck by lightning. The fluid knocked off the top of the chimney, then ran on an iron brace leading from the chimney to the roof, where it entered the house, making a hole about four feet square, and tearing off all the plastering in the attic. It then ran down a zinc spout, and made a passage about a foot square through the wall into the cellar, without doing any farther damage to the building. A man at work in the second story of the house, and two others about fifteen rods from the building, were knocked down; all of them recovered in a short time.